Thanks again for your interest in the Kasey Altman hackathon to find the best next treatment for this rare cancer patient. This is our weekly update (#16), especially for those who were unable to join us in person for our last meetings on September 23 and 30.
As we are in the final weeks of this hackathon, we have focused on the prioritization of treatments for Kasey. Tessa Marcus, David Shalinsky, and Delsee walked through Kasey’s contingency plans (should she have a recurrence after her personalized vaccine) including a strategy that sits on top of specific treatment recommendations, and a consensus on combining an immunotherapy (such as a checkpoint inhibitor) with a treatment targeted on Kasey’s mutations (such as B7H3).
(For more on Kasey’s treatment options and priorities, please review the following documents: The list of treatment options, The presentation that was used to structure the prioritization panel conversation
We also discussed ways we (the hackathon crowd) could help accelerate the delivery of Kasey’s personalized cancer vaccine, which had been slowed due to issues in manufacturing at one of the vendors in the supply chain. Bill Paseman encouraged a deeper understanding of the process and vendors and contacting them and their suppliers.
Please see the recordings below for more details.
In Closing: Our Request
Please look for and fill out the survey on the hackathon process.
Best,
Kasey Altman, Delsee Altman, Lupe Montes, and Brad Power